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. 2006 Mar 6;34(5):1416–1426. doi: 10.1093/nar/gkl010

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© The Author 2006. Published by Oxford University Press. All rights reserved

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A model illustrating connections among cell cycle checkpoints, centrosome duplication, DNA damage repair, genetic instability, DNA damage response, developmental abnormalities and tumorigenesis caused by BRCA1 deficiency.