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. 2006 Mar 6;34(5):1416–1426. doi: 10.1093/nar/gkl010

Table 1.

A list of BRCA1 interacting proteins

Biological functions Interacting proteins
DDR and repair MSH2, MSH6, MLH1, ATM, BLM and the RAD50-MRE11-NBS1, DNA replication factor C, RAD51, Fanconi anemia proteins, PCNA, H2AX, c-Abl, MDC1
Tumor suppressors ATM, ATR, p53, BRCA2, RB, BARD1, BACH1
Oncogenes c-Myc, casein kinase II, E2F1, E2F4, STK15, AKT
Transcription RNA polymerase II holoenzyme (RNA helicase A, RPB2, RPB10α), CBP/p300, HDC and CtIP, estrogen receptor α, androgen receptor, ZBRK1, ATF1, STAT1, Smad3, BRCT-repeat inhibitor of hTERT expression (BRIT1)
Cell cycle related Ayclin A, Cyclin D1, Cyclin D1, CDC2, Cdk2, Ckd4, γ-tublin, p21, p27
Stress response, apoptosis MEKK3, IFI16, X-linked inhibitor of apoptosis protein (XIAP)
Others BAP1, BIP1, BRAP2, importin α