Table 1.
Cell line | No. of cells | Breaks | Gaps | Isochromatid breaks | Asymmetrical and symmetrical exchanges | Dicentrics | Centric rings |
---|---|---|---|---|---|---|---|
51D1Lox | 351 | 0.07 ± 0.04 | 0.7 ± 0.1 | 0.1 ± 0.05 | 0 | 0.003 | 0 |
51D1.3 (BAC) | 350 | 0.03 ± 0.03 | 0.8 ± 0.1 | 0.15 ± 0.07 | 0 | 0 | 0 |
51D1 | 353 | 0.36 ± 0.09 | 2.2 ± 0.2 | 0.7 ± 0.1 | 0.04 | 0.003 | 0.01 |
Fold increase 51D1 vs. 51D1Lox | 5.1b | 3.4** | 6.6** | — | 1 | — | |
Fold increase 51D1 vs. 51D1.3 | 12c | 2.8* | 4.9* | — | — | — |
*Indicates P < 0.05 and ** for P < 0.01 using the student t-test.
aValues are given as mean number of aberrations per cell ± SEM. Each value is based on the data in three experiments.
bP = 0.11.
cP = 0.09.