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. 2006 Mar 3;34(5):1342–1350. doi: 10.1093/nar/gkl022

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© The Author 2006. Published by Oxford University Press. All rights reserved

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Growth delay and decreased survival in ΔNter mice. (A) Growth curve for male ZBP-89^FL/FL (gray dashed line, n = 20), ZBP-89^FL/ΔN (black dotted line, n = 36), and ZBP-89^ΔN/ΔN (black solid line, n = 16) offspring. A similar pattern was seen with female mice (not shown). ** P < 0.01; * P < 0.05. A trend toward lower body weights in ZBP-89^ΔN/ΔN persisted after 12 weeks, but was no longer statistically significant (data not shown). (B) Kaplan–Meier analysis of survival interval to the onset of morbidity or death. (C) Semi-quantitative RT–PCR analysis of ZBP-89^FL and ZBP-89^ΔN mRNA levels in the colon.