Fig. 3. Mitochondrial Ca²⁺ buffering regulates the extent of I_CRAC evoked by thapsigargin in weak Ca²⁺ buffer. (A) Time courses of development of I_CRAC following dialysis with thapsigargin alone (filled circles), thapsigargin plus cocktail (open circles) and thapsigargin alone after exposure to antimycin A and oligomycin (open diamonds) are shown. (B) Current–voltage relationships for the cells shown in (A) are depicted, taken when the whole-cell currents had reached steady state. (C) Bar chart plotting mean data for the three conditions. *p < 0.01.