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. 2002;2(1):31–36. doi: 10.1155/S1110724302000347

Table 1.

Location of the brain isoforms of dystrophin throughout the brain.


Dystrophin isoform Cellular location

Dp427-M Glia and vascular endothelial cells

Dp427-C Cortical and hippocampal (CA 1-3 region) pyramidal neurons

Dp427-P Fetal cerebral cortex and mature cerebellar purkinje cells

Dp140 Astroglial processes throughout the neuropil during development
Leptomeningeal surfaces and along penetrating blood vessels
Ensheathing the olfactory nerve
Neurohypophysis

Dp116 Late human fetal brain
Caudate/putamen region

Dp71 Early embryonic stem cells
Mesenchymal-epithelial interactions
Embryonic midbrain and hindbrain
Perinatal brain at stages of terminal neural differentiation
Early embryonic forebrain continuing until adult life
Cerebral cortex
Granule neurons of dentate gyrus of hippocampus
Neocortial regions (neurogenesis and synaptic plasticity)
Olfactory bulb
Pituitary gland
Retina