Table 1.
Association of glutathione S-transferase (GST)M1 genotype and clinicopathological data of breast cancer patients studied
| GSTM1 | |||||
| Parameters | Variables | Present | Null | OR (95% Cl) | |
| Age (years) | >50 | 22 | 28 | ||
| >50 | 17 | 25 | 1.99 (0.531-7.44) | ||
| Status | Premenopausal | 22 | 23 | ||
| Postmenopausal | 17 | 30 | 0.59 (0.22-1.61) | ||
| Clinical tumour size | T2 | 15 | 16 | ||
| T3 + T4 | 24 | 37 | 1.7 (0.62-4.52) | ||
| Clinical nodal involvement | N0 | 14 | 11 | ||
| N1 + N2 | 25 | 42 | 3.02 (0.97-9.89) | ||
| Histologic grade | SBR1 | 8 | 6 | ||
| SBR2 + 3 | 31 | 47 | 2.4 (0.66-9.02) | ||
| Hormone receptors | HR- | 17 | 19 | ||
| HR+ | 22 | 34 | 1.04 (0.38-2.80) | ||
| Pathological tumour size | pT0 + pT1 | 19 | 26 | ||
| pT2 + pT3 | 20 | 24 | 0.8 (0.32-2.08) | ||
| Involved nodes | pN- | 10 | 9 | ||
| pN1+ pN3+ | 29 | 54 | 2.05 (0.67-6.27) | ||
| p53 | Normal | 31 | 33 | ||
| Mutated | 8 | 20 | 2.7 (0.88-7.90) | ||
CI, confidence interval; OR, odds ratio.