Table 5.

Proportions of BRCA1 and BRCA2 mutations in 19 male breast cancer probands classified by number of cancer patients in the family and age at disease diagnosis

	Age of proband at disease diagnosis
	41-50 years		51 years or more		All ages
Cancer patients	BRCA1	BRCA2	BRCA1	BRCA2	BRCA1	BRCA2
in family*	[% (n)]	[% (n)]	[% (n)]	[% (n)]	[% (n)]	[% (n)]
One	0 (0/1)	0 (0/1)	0 (0/13)	8 (1/13)	0 (0/14)	7 (1/14)
Two or three	0 (0/3)	0 (0/3)	0 (0/2)	50 (1/2)	0 (0/5)	20 (1/5)
Total	0 (0/4)	0 (0/4)	0 (0/15)	13 (2/15)	0 (0/19)	10 (2/19)

^*Including proband; numbers of BRCA1- and BRCA2-positive cases over number of cases in each age subset are given in brackets.