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Isolated and sequenced FGFR2 isoforms from SUM-52PE. Isolated FGFR2 variants had variable expression of two to three Ig-like domains, as well as the characteristic acid box in the extracellular portion of the molecule. Variability between isolated clones also existed in the intracellular portion of the molecule, where alternative splicing of exons C1/C2 or C3 created either a full-length carboxyl termini (C1), or truncated versions (C2 or C3).
