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. 2000 Jun 19;2(5):378–385. doi: 10.1186/bcr82

Table 2.

Association of AIB1 genotype and breast cancer risk, Nurses' Health Study 1989-1994

Premenopausal Cases Controls OR* 95% CI
No of alleles with 26 or fewer repeats

0 49 51 1.00
1 14 16 0.91 0.40-2.09
2 1 3 0.32 0.03-3.25
1 or 2 15 19 0.82 0.37-1.81

Postmenopausal Cases Controls OR 95% CI

No of alleles with 26 or fewer repeats

0 275 397 1.00
1 75 106 1.04 0.74-1.46
2 8 7 1.90 0.67-5.42
1 or 2 83 113 1.09 0.78-1.52

Combined analysis Cases Controls OR§ 95% CI

No of alleles with 26 or fewer repeats

0 361 476 1.00
1 94 129 0.99 0.73-1.35
2 9 10 1.29 0.52-3.23
1 or 2 103 139 1.01 0.75-1.36

AIB1 genotype

29/29 92 141 1.00
28/29 196 227 1.27 0.91-1.77
28/28 64 95 0.99 0.65-1.50
26/29 47 69 1.04 0.66-1.64
26/28 45 55 1.23 0.75-2.02
26/26 9 10 1.48 0.57-3.81

*Unconditional logistic regression adjusted for the matching variables: age, date of blood sampling, time of blood sampling and fasting status. Unconditional logistic regression adjusted for the matching variables: age, postmenopausal hormone use, date of blood sampling, time of blood sampling and fasting status. Nine controls were excluded due to incomplete matching. §Conditional logistic regression adjusted for the matching variables: age, menopausal status, postmenopausal hormone use, date of blood sampling, time of blood sampling and fasting status. Genotypes combined and modeled together, but not included in table (cases, controls): 19/29 (0, 1), 22/29 (0, 1), 25/28 (0, 1), 25/29 (1, 0), 26/30 (1, 2), 27/28 (2, 1), 27/29 (1, 2), 28/30 (2, 3), 28/31 (1, 1), 28/34 (1, 0), 29/30 (1, 5), and 29/31 (1, 1).