Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2002 Dec 13;99(26):16881–16886. doi: 10.1073/pnas.252570299

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2002, The National Academy of Sciences

PMC Copyright notice

Fig 3. — Regenerating Alb-Cre Foxm1b^−/− mouse liver displays significant decreases in hepatocyte DNA replication and mitosis. (A) Graphic representation of diminished BrdUrd incorporation during mouse liver regeneration in Foxm1b-deficient hepatocytes. Graphically presented is the BrdUrd incorporation (DNA replication) detected by immunohistochemical staining (10, 25) at the indicated hours after PHx with either 8-week-old Alb-Cre Foxm1b^−/− mice or Foxm1b fl/fl littermates. The mean of the number of BrdUrd-positive hepatocyte nuclei per 1,000 hepatocytes ± SE was calculated for each time point (three mice per time point). (B) Graphic representation of diminished hepatocyte mitosis in regenerating livers of Foxm1b-deficient vs. fl Foxm1b mouse liver between 32 and 52 h after PHx. Hepatocyte mitosis is expressed as the mean of the number of mitotic figures found per 1,000 hepatocytes ± SD using three mice per time point (10, 25).