FIG. 1.

Schematic representation of the SeM protein of S. equi. Amino acids 37 to 352 are required for fibrinogen binding (16). Amino acids 1 to 37 contain the M-protein signal sequence (ss) (31). Amino acids 37 to 184 (deleted) were found to be absent from 24% of S. equi strains isolated from outwardly healthy horses (3). Amino acids 226 to 406 (central repeat region) contain the A and B repeat regions (31). Amino acids 482 to 534 contain the wall-spanning region and “LPSTG” cell wall anchor (cwa) (31). Amino acids 71 to 421 are required for IgG binding (17).