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. 2006 Mar;44(3):688–692. doi: 10.1128/JCM.44.3.688-692.2006

TABLE 2.

Drug susceptibility test results of phase Ia

Drug and concn (μg/ml) No. of strains for which the indicated concn is the MIC
Total no. (%) of tests
Site 1
Site 2
Site 3
MGIT 460 MGIT 460 MGIT 460 MGIT 460
Amikacin
    ≤0.5 10 10 10 10 10 10 30 (100) 30 (100)
    1.0 0 0 0 0 0 0 0 0
    2.0 0 0 0 0 0 0 0 0
Capreomycin
    0.625 1 3 9 10 0 10 10 (33.3) 23 (76.7)
    1.25 8 7 1 0 10 0 19 (63.3) 7 (23.3)
    2.5 1 0 0 0 0 0 1 (3.3) 0
Ethionamide
    ≤0.625 3 5 7 8 6 8 16 (53.3) 21 (70.0)
    1.25 4 2 0 1 2 1 6 (20.0) 4 (13.3)
    2.5 2 3 1 0 1 0 4 (13.3) 3 (10.0)
    >2.5 1 0 2 1 1 1 4 (13.3) 2 (6.7)
Ofloxacin
    ≤1.0 10 10 10 10 10 10 30 (100) 30 (100)
    2.0 0 0 0 0 0 0 0 0
    4.0 0 0 0 0 0 0 0 0
Rifabutin
    ≤0.25 10 10 10 10 10 10 30 (100) 30 (100)
    0.5 0 0 0 0 0 0 0 0
    1.0 0 0 0 0 0 0 0 0
Linezolid
    ≤0.5 5 5 5 10 10 8b 20 (66.7)b 23 (76.7)b
    1.0 5 5 4 0 0 1 9 (30.0) 6 (20.0)
    2.0 0 0 1 0 0 0 1 (3.3) 0
a

Ten strains were tested. MGIT, MGIT 960; 460, BACTEC 460.

b

Results for one test missing.