TABLE 2.
Virological characteristic of genotype C HBV strains with different configurations at nucleotides 1856 to 1858a
| Mutation | No. (%) of isolates with:
|
P value for TCC vs CCC | No. (%) of isolates with CTC (n = 6) | P value for TCC vs CTC | No. (%) of isolates with CCT (n = 62) | P value for TCC vs CCT | |
|---|---|---|---|---|---|---|---|
| TCC (n = 67) | CCC (n = 79) | ||||||
| A1762T | 45 (67) | 58 (73) | 0.41 | 4 (67) | 0.98 | 34 (55) | 0.15 |
| G1764A | 48 (71) | 60 (76) | 0.55 | 5 (83) | 0.54 | 35 (57) | 0.072 |
| G1896A | 0 (0) | 0 (0) | 0 (0) | 28 (45) | <0.001 | ||
| G1897A | 0 (0) | 0 (0) | 6 (100) | <0.001 | 0 (0) | ||
| G1898A | 43 (64) | 1 (1) | <0.001 | 0 (0) | 0.002 | 0 (0) | <0.001 |
| G1899A | 3 (5) | 3 (4) | 0.84 | 0 (0) | 0.60 | 10 (16) | 0.028 |
a
The prevalence of mutations among different HBV isolates was compared to that among HBV isolates with TCC at nucleotides 1856 to 1858.