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. 2006 Mar;44(3):1197–1201. doi: 10.1128/JCM.44.3.1197-1201.2006

TABLE 2.

Clinical information and IFN-γ ELISPOT results of study subjectsa,b

Codec BCG TST (mm) TB Treatment PPDe
ESAT-6e
CFP-10e
TB37.6e
TB7.7e
Yr 0 Yr 1 Yr 0 Yr 1 Yr 0 Yr 1 Yr 0 Yr 1 Yr 0 Yr 1
A Yes 20 No Yes 275 76 71 78 469 190 52 < 7 <
B No 25 No Yes 146 160 370 275 104 148 53 8 5 <
C Yes 3 No No 5 98 < 9 < < < < 0 <
D No 0 No No 12 16 6 3 4 1 1 1 0 8
E Yes ND No No 27 23 7 < 7 4 6 0 6 <
F Yes ND No No * * * * * * * * * *
G Yes >10 No No < 5 5 11 <
H No 0 No No 5 42 < 4 < < < < < <
I No 0 No No 46 < < 1 2
Lab 1 No 0 No No < < < < 2
Lab 2 Yes 0 No No 15 < < < <
Lab 3 Yes 0 No No 2 < < < 3
Lab 4 Yes 22 No No 14 < < < <
Lab 5 No >10 No No 0 < < < <
Lab 6 Unknown >10 No No 271 27 7 < 19
Lab 7 No >10 No Yes 3 < < < <
Lab 8 No 11 No No 6 < < < <
Lab 9 Yes ND Cured TBd Yes 22 < < 3 <
Lab 10 Yes 11 Cured TBd Yes 17 < < < <
TB 1 No ND Cured TB Yes 144 18 19 5 12
TB 2 Unknown ND Cured TB Yes 52 84 34 < 16
TB 3 No ND Cured TB Yes 196 63 104 < 3
TST 1 No >10 No Yes 325 35 275 < <
TST 2 No >10 No Yes 243 77 111 2 115
TST 3 No >10 No Yes 181 324 240 7 16
a

IFN-γ ELISPOT was done 4 months (year 0) and 16 months (year 1) after the accidental exposure. ELISPOT results are shown as mean numbers of spot-forming cells (SFC)/106 PBMC minus the mean of medium value.

b

Symbols: <, number of SFC less than in medium; ND, not done; *, not interpretable due to high medium values.

c

A to I, technicians present during the accident, by decreasing exposure level; Lab 1 to 10, technicians not present during the accident; TB 1 to 3, cured TB patients, treated 10, 3, and 2 years before; TST 1 to 3, tuberculin skin test converters after a known exposure to TB 5, 6, and 10 years before.

d

Limited pulmonary TB diagnosed during routine checkup before clinical symptoms became apparent; Lab 9, 33 years ago and Lab 10, 8 years ago.

e

A value that is >20 constitutes a positive response.