TABLE 1.

Invasive pneumococcal disease incidence in 1999 and 2002^a

Serotype(s)	Age group (yr)	1999		2002		Change in rate	P valuec
		No. of cases	Rateb	No. of cases	Rate
All	<5	1,167	96.36	308	24.05	−72.31	<0.001
	≥5	3,141	19.08	2,418	13.72	−5.36	<0.001
	All	4,308	24.37	2,726	14.42	−10.05	<0.001
PCV7 serogroups except 19A	<5	1,064	87.85	143	11.16	−76.69	<0.001
	≥5	2,067	12.55	1,233	7.00	−5.55	<0.001
	All	3,131	17.71	1,376	7.28	−10.43	<0.001
Non-PCV7 serogroups plus 19A	<5	103	8.50	165	12.88	+4.38	<0.001
	≥5	1,067	6.48	1,185	6.72	+0.24	0.4
	All	1,170	6.62	1,350	7.14	+0.52	0.06

^aThe surveillance areas included California (San Francisco only), Connecticut (state), Georgia (the 20-county Atlanta metro area), Maryland (the 7-county Baltimore II area), Minnesota (the 7-county Twin Cities area), New York (the 15-county Albany and Rochester areas), Oregon (the 3-county Portland area), and Tennessee (4 counties).

^bNumber of cases per 100,000 individuals.

^cP values are for 1999 versus 2002.