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. 2006 Mar;72(3):2191–2199. doi: 10.1128/AEM.72.3.2191-2199.2006

TABLE 2.

Frequencies of intentional mutations in different types of clones

Clone typea No. of mutations per clone
Nonsilent Silent Total
Random 4.94b 1.41b 6.35b
Random (20) 4.10 1.35 5.45
Active (43) 1.70 1.42 3.12
CB selected (10) 2.00 1.50 3.50
a

Numbers of sequenced clones are given in parentheses.

b

As calculated for the specific sequence and degree of degeneracy of the mutagenic oligonucleotides (theoretical value).