TABLE 2.
Clone typea | No. of mutations per clone
|
||
---|---|---|---|
Nonsilent | Silent | Total | |
Random | 4.94b | 1.41b | 6.35b |
Random (20) | 4.10 | 1.35 | 5.45 |
Active (43) | 1.70 | 1.42 | 3.12 |
CB selected (10) | 2.00 | 1.50 | 3.50 |
Numbers of sequenced clones are given in parentheses.
As calculated for the specific sequence and degree of degeneracy of the mutagenic oligonucleotides (theoretical value).