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. 2006 Feb 9;6:2. doi: 10.1186/1471-2490-6-2

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Copyright © 2006 Randich et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Enhancement of nociceptive responses to urinary bladder distension (UBD). Panel A presents group mean EMG as a function of UBD pressure – a typical EMG response to a 60 mm Hg UBD is given as an inset. The 24 hr zymosan-treated group differed significantly (p < 0.05) from the naive and saline control groups as denoted by *. Panel B presents group mean ABP as a function of UBD – a typical pressor response to a 60 mm Hg UBD is given as an inset. The 24 hr zymosan-treated group differed significantly from the naive and saline control groups as denoted by *. In A & B all other comparisons were not statistically significant. Note: the number of subjects given in B is less than those in A due to occasional technical difficulty with ABP measurements. Symbols are per inset legend (controls with open symbols; zymosan-treated with filled symbols). Error bars indicate SEM.