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. 2006 Feb 17;5:4. doi: 10.1186/1476-0711-5-4

Table 1.

Frequency of isolation and cell numbers of organisms from vaginal samples related to vaginal pH

Determined vaginal pH


Organisms < 4.5 ≥ 4.5


Frequency of isolation1 No. of organisms2 Frequency of isolation1 No. of organisms2
Aerobic flora
Total aerobes3 109/115 7.20 ± 0.37 65/82 6.65 ± 1.57
Lactobacillus spp. 107/115 7.69 ± 1.61 61/82 6.58 ± 1.88
H2O2-positive lactobacilli 102/115 7.77 ± 1.53 56/82 6.46 ± 1.87
H2O2-positive lactobacilli (>108 CFU/ml) 64/115 8.72 ± 0.43 26/826 8.42 ± 0.65
Anaerobic flora
Total anaerobic isolates 5/115 7.71 ± 0.32 9/82 8.06 ± 0.12
Bifidobacterium spp. 3/115 8.03 ± 0.42 5/82 7.94 ± 0.64
Bacteroides spp. 2/115 7.39 ± 0.09 4/82 8.19 ± 0.53
Prevotella spp. 0/115 n.d.4 0/82 n.d.4
Molecular detection
Gardnerella vaginalis 26/115 -5 25/82 -5
Candida spp. 28/115 -5 18/82 -5
Trichomonas vaginalis 0/115 -5 0/82 -5
Atopobium vaginae 0/115 -5 11/826 -5

1 Values are numbers of observations/numbers of subjects

2 Values are log10 CFU/ml sample ± standard deviations

3 Including Coliform spp., Staphylococcus spp. and Staphylococcus spp.

4 not detected

5 no cell counts can be given due to the used methods (hybridisation and PCR, respectively)

6 P < 0.05 when compared to values for normal pH using the chi-square procedure