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Electron microscopy of virus particles. Shown are negative-stained images of HPIV3 (A), HPIV3/Ebo-GP (B), HPIV3/EboGP-NP (C), and EV (D). Glycoprotein peplomers are seen as a fringe along the outer edge of all virus particles, and extruding nucleocapsid is evident in panel B. Representative images are shown; in general, consistent differences between HPIV3 and its derivatives with EV gene inserts were not evident.
