Alignment of Cps19fB with Streptococcus agalactiae CpsB (Sagal-CpsB; GenBank accession number AF163833), Streptococcus salivarius CpsB (Ssali-CpsB; Y17900), Streptococcus thermophilus EpsB (Sther-EpsB; U40830), Streptococcus suis Cps2D (Ssuis-Cps2D; AF118389), Staphylococcus aureus Cap8C (Saure-Cap8C; U73374), Bacillus subtilis YwqE (Bsubt-YwqE; Z92952), and Lactococcus lactis EpsC (Llact-EpsC; AF036485). The four conserved motifs are underlined, and identical residues are shaded; the asterisks indicate amino acids predicted to be essential for function. The arrows indicate amino acids mutated in Rx1-19F-BNQ, and the absence of a residue is indicated by a period.