TABLE 2.
MICs for the clinical strains included in this study
Isolate no. | pI | MIC (μg/ml) ofa:
|
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
AMX | AMC | FOX | AT | CTX | CTX-CL | CAZ | CAZ-CL | IMP | MRP | CEP | ||
1 | 5.4, 8.0 | >256 | 4 | 8 | 4 | 24 | 0.094 | 1.5 | 0.25 | 0.25 | 0.016 | 2 |
2 | 8.0 | >256 | 4 | 2 | 2 | 24 | 0.047 | 1.0 | 0.094 | 0.25 | 0.016 | 2 |
3 | 8.0 | >256 | 6 | 4 | 3 | 16 | 0.064 | 1.0 | 0.25 | 0.25 | 0.016 | 2 |
3 (Tc)b | 8.0 | >256 | 4 | 4 | 3 | 32 | 0.047 | 1.0 | 0.125 | 0.125 | 0.032 | 4 |
4 | 5.4, 8.0 | >256 | 4 | 2 | 0.75 | 16 | 0.023 | 0.5 | <0.064 | 0.094 | 0.012 | 1.5 |
5 | 5.4, 8.0 | >256 | 4 | 12 | 2 | 48 | 0.094 | 1.0 | 0.125 | 0.125 | 0.023 | 4 |
6 | 5.4, 8.0 | >256 | 4 | 4 | 2 | 24 | 0.047 | 0.75 | 0.125 | 0.19 | 0.016 | 2 |
7 | 8.0 | >256 | 4 | 2 | 2 | 24 | 0.032 | 1.0 | 0.064 | 0.19 | 0.012 | 1.5 |
8 | 8.0 | >256 | 4 | 4 | 2 | 16 | 0.064 | 1.0 | 0.125 | 0.125 | 0.016 | 4 |
9 | 5.4, 8.0 | >256 | 8 | 24 | 8 | >128 | >1.0 | 6.0 | 4.0 | 0.25 | 0.023 | 4 |
10 | 5.4, 8.0 | >256 | 6 | 12 | 2 | 64 | 0.094 | 1.0 | 0.125 | 0.125 | 0.016 | 4 |
11 | 5.4, 8.0 | >256 | 4 | 3 | 2 | 32 | 0.047 | 1.0 | 0.064 | 0.25 | 0.016 | 4 |
12 | 8.0 | >256 | 4 | 4 | 2 | 64 | 0.047 | 1.0 | 0.094 | 0.19 | 0.016 | 4 |
13 | 8.0 | >256 | 4 | 4 | 4 | >128 | 0.047 | 1.0 | 0.094 | 0.125 | 0.012 | 2 |
14 | 8.0 | >256 | 4 | 4 | 2 | 48 | 0.064 | 1.5 | 0.19 | 0.125 | 0.012 | 4 |
15 | 8.0 | >256 | 4 | 3 | 1.5 | >128 | 0.047 | 1.0 | 0.125 | 0.19 | 0.016 | 4 |
16 | 5.4, 8.0 | >256 | 4 | 4 | 2 | 16 | 0.064 | 1.0 | 0.19 | 0.19 | 0.023 | 2 |
17 | 8.0 | >256 | 4 | 4 | 2 | 24 | 0.064 | 1.0 | 0.125 | 0.125 | 0.012 | 2 |
18 | 5.4, 8.5 | >256 | 4 | 2 | 8 | 24 | >1 | >32 | >4 | 0.25 | 0.032 | 0.38 |
19 | 5.4 | >256 | 16 | 16 | 24 | 0.5 | 0.19 | >32 | 0.75 | 0.25 | 0.032 | 2 |
20 | 5.4 | >256 | 2 | 1 | 0.5 | <0.016 | <0.016 | 12 | 0.064 | 0.19 | 0.023 | 0.032 |
21 | 5.4 | >256 | 4 | 12 | 6 | 0.5 | <0.016 | >32 | 0.19 | 0.125 | 0.023 | 0.75 |
22 | 9.0 | >256 | 4 | 2 | 4 | >256 | 0.047 | 6 | 0.094 | 0.125 | 0.016 | 8 |
23 | 9.0 | >256 | 12 | >256 | >256 | >256 | >1.0 | >32 | >4 | 0.125 | 0.064 | >128 |
24 | 9.0 | >256 | 12 | >256 | >256 | >256 | >1.0 | >32 | >4 | 0.125 | 0.047 | 128 |
25 | 5.9 | >256 | 4 | 2 | 1 | 2 | 0.094 | 2 | 0.19 | 0.5 | 0.032 | 0.094 |
26 | 5.4, 5.9 | >256 | 4 | 8 | 6 | 0.19 | 0.047 | >32 | 0.125 | 0.125 | 0.016 | 0.5 |
27 | 7.6 | >256 | 8 | 4 | 0.125 | 0.064 | 0.032 | 4 | 0.19 | 0.19 | 0.032 | 0.5 |
28c | 7.4 | >256 | 4 | 1 | 6 | 24 | <0.016 | >32 | 0.19 | 0.19 | 0.032 | 3 |
29c | 7.9 | >256 | 4 | 12 | 6 | 0.5 | 0.064 | >32 | 0.19 | 0.125 | 0.023 | 0.75 |
30c | 7.4 | >256 | 6 | 2 | 1 | 1 | 0.047 | 1.5 | 0.125 | 0.19 | 0.032 | 0.094 |
E. coli TG1 | 3 | 3 | 2 | 0.047 | 0.023 | 0.023 | 0.064 | 0.064 | 0.125 | 0.032 | 0.094 | |
E. coli TG1 (pC)d | 8.0 | >256 | 6 | 2 | 48 | >256 | 0.064 | 4 | 0.125 | 0.19 | 0.023 | 64 |
AMX, amoxicillin; AMC, amoxicillin-clavulanic acid; FOX, cefoxitin; AT, aztreonam; CTX, cefotaxime; CTX-CL, cefotaxime-clavulanic acid; CAZ, ceftazidime; CAZ-CL, ceftazidime-clavulanic acid; IMP, imipenem; MRP, meropenem; CEP, cefepime.
This isolate corresponds to the transconjugant of clinical strain 3.
This isolate corresponds to K. pneumoniae.
E. coli transformed with plasmid pC, which carries the CTX-M-14 gene.