TABLE 2.
Possible cases of laboratory cross-contamination detailing symptoms, therapy, and final diagnosis
| Case | Reason investigateda | Anti-TB drugs | Assessment conclusion |
|---|---|---|---|
| M | CXR—upper zone shadowing, cavitation; clinically consistent | Full course | Presumed case of TB; no obvious epidemiological link to clustered cases possible laboratory contamination between two known cases |
| N | CXR—upper zone shadowing and effusion; pleuritic chest pain | Full course | Treated as case of TB; symptoms and signs persisted posttreatment |
| O | Fine-needle aspirate of persisting lymphadenopathy | Unknown | Unknown—case notes lost |
| P | CXR—upper zone shadowing; clinically consistent | Full course | Presumed case of TB; no obvious epidemiological link to clustered cases: possible laboratory contamination between two known cases |
| Q | CXR—effusion, pneumothorax; breathless, cachexia, persistent cough | Unknown | Known congestive cardiac failure and carcinoma of bronchus; diagnosis of TB uncertain; already transferred abroad for terminal care before culture result |
| R | Unknown | Unknown | Case notes unobtainable |
| S | HIV positive, low CD4 counts, febrile, cough | Full course | Multiple other samples isolated MAIC; probably not TB but possibility of dual infection, hence not denotified |
| T | CXR—pleural effusion; immunocompromised post-renal transplant; past history of TB | Full course | Current diagnosis uncertain; fully treated in view of past history and immunocompromise |
CXR, chest X ray; HIV, human immunodeficiency virus; MAIC, Mycobacterium avium-M. intracellulare complex; TB, tuberculosis.