TABLE 1.
Serotype 5 S. pneumoniae isolates from Argentina, Brazil, Colombia, Guatemala, Mexico, and Uruguay
| Code | Country codea | Yr | MIC (μg/ml) ofb:
|
ET | PFGE type | ||
|---|---|---|---|---|---|---|---|
| TET | CHL | STX | |||||
| 1032 | ARG708 | 1995 | 0.12 | 4 | 1/19 | 1 | A5 |
| 1033 | ARG741 | 1995 | 4 | 4 | 1/19 | 1 | A5 |
| 1034 | ARG746 | 1995 | 0.25 | 4 | 1/19 | 1 | A5 |
| 1035 | ARG793 | 1995 | 0.12 | 4 | 1/19 | 1 | A5 |
| 1036 | ARG1033 | 1996 | 0.12 | 4 | 1/19 | 1 | A5 |
| 1037 | ARG1043 | 1996 | 0.25 | 4 | 2/38 | 1 | A5 |
| 1038 | ARG1061 | 1996 | 0.12 | 4 | 1/19 | 1 | A5 |
| 1039 | ARG1096 | 1996 | 0.5 | 4 | 1/19 | 1 | A5 |
| 1040 | ARG1105 | 1996 | 0.25 | 4 | 1/19 | 1 | A5 |
| 1041 | ARG1107 | 1996 | 0.25 | 4 | 2/38 | 1 | A5 |
| 1042 | ARG1108 | 1996 | 16 | 2 | 1/19 | 2 | A6 |
| 1043 | ARG1119 | 1996 | 0.25 | 4 | 2/38 | 1 | A5 |
| 1044 | ARG1127 | 1996 | 0.25 | 4 | 2/38 | 1 | A5 |
| 1045 | ARG1128 | 1996 | 0.25 | 4 | 2/38 | 1 | A5 |
| 1046 | ARG1152 | 1996 | 0.25 | 4 | 2/38 | 1 | A5 |
| 1047 | ARG1157 | 1996 | 0.25 | 4 | 2/38 | 1 | A5 |
| 1048 | ARG1164 | 1996 | 0.25 | 4 | 1/19 | 1 | A5 |
| 1049 | ARG1179 | 1997 | 16 | 2 | 0.25/4.7 | 1 | A5 |
| 1050 | ARG1180 | 1997 | 8 | 2 | 4/76 | 2 | A6 |
| 1051 | ARG1182 | 1997 | 16 | 2 | 0.25/4.7 | 1 | A5 |
| 1153 | ARG1206 | 1997 | 32 | 4 | 1/19 | 1 | A5 |
| 1054 | ARG1224 | 1997 | 0.12 | 4 | 2/38 | 1 | A5 |
| 1055 | ARG1240 | 1997 | 0.12 | 4 | 1/19 | 1 | A5 |
| 1010 | BRA56 | 1996 | 2 | 4 | 0.25/4.7 | 2 | A6 |
| 1011 | BRA57 | 1996 | 8 | 4 | 8/152 | 1 | A |
| 1012 | BRA71 | 1996 | 0.5 | 2 | 0.25/4.7 | 2 | A6 |
| 1013 | BRA102 | 1996 | 16 | 4 | 8/152 | 1 | A |
| 1015 | BRA169 | 1997 | 16 | 4 | 8/152 | 1 | A |
| 1016 | BRA171 | 1997 | 32 | 4 | 8/152 | 1 | A2 |
| 1017 | BRA210 | 1997 | 0.25 | 4 | 1/19 | 1 | A7 |
| 1009 | BRA39 | 1997 | 0.12 | 4 | 0.25/4.7 | 1 | A7 |
| 1020 | BRA410 | 1997 | 16 | 4 | 8/152 | 1 | A |
| 1018 | BRA213 | 1998 | 16 | 4 | 16/302 | 1 | A |
| 1019 | BRA291 | 1998 | 16 | 4 | 8/152 | 1 | A |
| 1007 | BRA5 | 1998 | 0.25 | 4 | 1/19 | 1 | A7 |
| 7 | COL7 | 1994 | 32 | 32 | 2/38 | 1 | A |
| 12 | COL12 | 1994 | 32 | 16 | 4/76 | 1 | A |
| 24 | COL24 | 1994 | 32 | 32 | 2/38 | 1 | A |
| 30A | COL30A | 1994 | 16 | 16 | 4/76 | 1 | A |
| 30B | COL30B | 1994 | 32 | 32 | 4/76 | 1 | A |
| 47 | COL47 | 1994 | 32 | 32 | 0.5/9.5 | 1 | A |
| 49A | COL49A | 1994 | 32 | 16 | 1/19 | 1 | A |
| 49C | COL49C | 1994 | 32 | 16 | 1/19 | 1 | A |
| 72 | COL72 | 1994 | 0.12 | 2 | 0.12/2.3 | 3 | A6 |
| 86 | COL86 | 1994 | 32 | 32 | 8/152 | 1 | A |
| 106 | COL106 | 1994 | 32 | 32 | 2/38 | 1 | A |
| 123 | COL123 | 1994 | 32 | 16 | 0.25/4.7 | 1 | A |
| 133 | COL133 | 1994 | 32 | 16 | 0.06/1.1 | 1 | A |
| 135 | COL135 | 1994 | 0.25 | 4 | 2/38 | 1 | A4 |
| 136 | COL136 | 1994 | 32 | 16 | 2/38 | 1 | A1 |
| 161 | COL161 | 1995 | 16 | 32 | 2/38 | 1 | A |
| 175 | COL175 | 1995 | 32 | 32 | 8/152 | 1 | A |
| 177 | COL178 | 1995 | 32 | 32 | 8/152 | 1 | A |
| 189 | COL190 | 1995 | 16 | 32 | 1/19 | 1 | A |
| 190 | COL191 | 1995 | 32 | 32 | 1/19 | 1 | A |
| 201 | COL202 | 1995 | 32 | 16 | 2/38 | 1 | A |
| 212 | COL213 | 1995 | 8 | 16 | 8/152 | 1 | A |
| 214 | COL215 | 1995 | 32 | 16 | 2/38 | 1 | A1 |
| 221 | COL222 | 1995 | 32 | 16 | 2/38 | 1 | A |
| 222 | COL223 | 1995 | 32 | 4 | 0.5/9.5 | 1 | A |
| 224 | COL225 | 1995 | 0.12 | 4 | 0.12/2.3 | 2 | A6 |
| 226 | COL227 | 1995 | 32 | 2 | 0.25/4.7 | 1 | A |
| 227 | COL228 | 1995 | 32 | 16 | 2/38 | 1 | A |
| 252 | COL253 | 1995 | 16 | 16 | 2/38 | 1 | A |
| 255 | COL256 | 1995 | 16 | 32 | 1/19 | 1 | A |
| 261 | COL262 | 1995 | 16 | 16 | 2/38 | 1 | A/PICK> |
| 282 | COL283 | 1995 | 16 | 16 | 0.06/1.1 | 1 | A |
| 283 | COL284 | 1995 | 16 | 16 | 1/19 | 1 | A |
| 299 | COL300 | 1995 | 16 | 16 | 0.06/1.1 | 1 | A |
| 303 | COL304 | 1995 | 16 | 16 | 0.25/4.7 | NDc | A |
| 316 | COL317 | 1996 | 32 | 32 | 8/152 | 1 | A |
| E1H | COLE1H | 1996 | 32 | 8 | 2/38 | 1 | A |
| E1LP | COLE1LP | 1996 | 32 | 32 | 2/38 | 1 | A |
| E16 | COLE16 | 1996 | 32 | 32 | 1/19 | 1 | A |
| E18 | COLE18 | 1996 | 32 | 32 | 4/76 | 1 | A |
| E45 | COLE45 | 1996 | 32 | 32 | 2/38 | 1 | A |
| E68 | COLE68 | 1996 | 32 | 32 | 2/38 | 1 | A1 |
| E72 | COLE72 | 1996 | 32 | 4 | 1/19 | 1 | A3 |
| E73 | COLE73 | 1996 | 32 | 32 | 2/38 | 1 | A |
| E86 | COLE86 | 1997 | 0.25 | 4 | 2/38 | 1 | A4 |
| E105 | COLE105 | 1997 | 32 | 32 | 2/38 | 1 | A |
| E149 | COLE145 | 1997 | 32 | 32 | 2/38 | 1 | A |
| E161 | COLE157 | 1997 | 0.12 | 4 | 2/38 | 1 | A8 |
| E178 | COLE174 | 1997 | 32 | 32 | 2/38 | 1 | A |
| E196 | COLE192 | 1998 | 0.25 | 4 | 2/38 | 1 | A8 |
| E225 | COLE220 | 1998 | 32 | 16 | 2/38 | 1 | A |
| E236 | COLE231 | 1998 | 32 | 16 | 8/152 | 1 | A |
| E324 | COLE318 | 1999 | 0.12 | 4 | 0.5/9.5 | 1 | A8 |
| E386 | COLE386 | 2000 | 32 | 16 | 32/608 | ND | A |
| E387 | COLE387 | 2000 | 32 | 16 | 16/304 | ND | A |
| E390 | COLE390 | 2000 | 16 | 16 | 2/38 | ND | A |
| E391B | COLE391B | 2000 | 16 | 16 | 1/19 | ND | A |
| 1878 | GUA168 | 1997 | 4 | 4 | 1/19 | ND | A |
| 1879 | GUA187 | 1997 | 8 | 4 | 4/76 | ND | A |
| 1880 | GUA753 | 1998 | 8 | 4 | 1/19 | ND | A14 |
| 1881 | GUA773 | 1998 | 8 | 4 | 1/19 | ND | A14 |
| 1882 | GUA783 | 1998 | 16 | 4 | 1/19 | ND | A15 |
| 1883 | GUA808 | 1998 | 8 | 4 | 1/19 | ND | A |
| 1884 | GUA811 | 1998 | 8 | 4 | 1/19 | ND | A |
| 1885 | GUA824 | 1998 | 4 | 4 | 1/19 | ND | A14 |
| 1886 | GUA1348 | 1998 | 8 | 4 | 1/19 | ND | A14 |
| 1887 | GUA1424 | 1998 | 16 | 4 | 1/19 | ND | A |
| 1025 | MEX49 | 1994 | 4 | 16 | 2/38 | 1 | A |
| 1026 | MEX110 | 1995 | 0.25 | 4 | 2/38 | 1 | A5 |
| 1027 | MEX111 | 1995 | 0.25 | 4 | 2/38 | 1 | A5 |
| 1028 | MEX112 | 1995 | 0.25 | 4 | 2/38 | 1 | A5 |
| 1029 | MEX115 | 1995 | 16 | 16 | 2/38 | 1 | A3 |
| 1023 | MEX10 | 1996 | 0.25 | 4 | 2/38 | 1 | A5 |
| 1024 | MEX16 | 1996 | 16 | 16 | 2/38 | 1 | A |
| 1030 | MEX146 | 1966 | 8 | 2 | 2/38 | 1 | A3 |
| 1021 | MEX2NM | 1998 | 0.25 | 4 | 0.5/9.5 | 1 | A5 |
| 1022 | MEX2PS | 1998 | 0.25 | 4 | 1/19 | 1 | A5 |
| 1215 | URU112 | 1988 | 8 | 2 | 0.25/4.7 | 2 | A12 |
| 1217 | URU185 | 1988 | 2 | 2 | 0.25/4.7 | 2 | A7 |
| 1216 | URU332 | 1989 | 8 | 4 | 0.25/4.7 | 2 | A12 |
| 1118 | URU96 | 1993 | 0.25 | 4 | 1/19 | 1 | A5 |
| 1119 | URU N48 | 1993 | 0.12 | 4 | 0.25/4.7 | 1 | A10 |
| 1120 | URU N649 | 1993 | 8 | 2 | 0.25/4.7 | 1 | A6 |
| 1121 | URU114 | 1994 | 0.25 | 4 | 1/19 | 1 | A5 |
| 1122 | URU139 | 1994 | 0.25 | 4 | 8/152 | 1 | A5 |
| 730 | URU168 | 1994 | 0.12 | 4 | 8/152 | 1 | A5 |
| 731 | URU173 | 1994 | 0.25 | 4 | 1/19 | 1 | A5 |
| 1123 | URU176 | 1994 | 0.25 | 4 | 8/152 | 1 | A5 |
| 1124 | URU181 | 1994 | 0.12 | 4 | 1/19 | 1 | A5 |
| 1125 | URU183 | 1994 | 0.25 | 4 | 2/38 | 1 | A5 |
| 732 | URU204 | 1994 | 0.25 | 4 | 2/38 | 1 | A5 |
| 733 | URU212 | 1994 | 4 | 2 | 0.12/2.3 | 1 | A5 |
| 1126 | URU216 | 1994 | 8 | 4 | 0.25/4.7 | 2 | A6 |
| 734 | URU227 | 1994 | 8 | 2 | 0.12/2.3 | 1 | A6 |
| 1127 | URU237 | 1994 | 8 | 2 | 0.25/4.7 | 2 | A6 |
| 735 | URU243 | 1994 | 0.25 | 4 | 1/19 | 1 | A9 |
| 1128 | URU252 | 1994 | 0.25 | 4 | 2/38 | 1 | A5 |
| 1129 | URU284 | 1995 | 0.12 | 4 | 0.5/9.5 | 1 | A5 |
| 1130 | URU297 | 1995 | 0.12 | 4 | 1/19 | 1 | A5 |
| 1131 | URU304 | 1995 | 0.25 | 4 | 2/38 | 1 | A5 |
| 736 | URU305 | 1995 | 8 | 4 | 0.12/2.3 | 1 | A5 |
| 1132 | URU316 | 1995 | 0.25 | 4 | 2/38 | 1 | A5 |
| 737 | URU325 | 1995 | 0.25 | 4 | 2/38 | 1 | A5 |
| 738 | URU350 | 1995 | 0.25 | 4 | 2/38 | 1 | A5 |
| 1133 | URU391 | 1995 | 8 | 4 | 0.25/4.7 | 2 | A6 |
| 1134 | URU392 | 1995 | 0.25 | 4 | 1/19 | 1 | A5 |
| 1135 | URU393 | 1995 | 0.12 | 4 | 2/38 | 1 | A5 |
| 739 | URU420 | 1996 | 8 | 4 | 0.25/4.7 | 1 | A6 |
| 740 | URU427 | 1996 | 0.12 | 4 | 4/76 | 1 | A5 |
| 742 | URU480 | 1996 | 0.12 | 4 | 1/19 | 1 | A5 |
| 743 | URU499 | 1996 | 0.12 | 4 | 1/19 | 1 | A5 |
| 1136 | URU504 | 1996 | 0.25 | 4 | 0.5/9.5 | 1 | A5 |
| 1137 | URU519 | 1996 | 0.25 | 4 | 1/19 | 1 | A5 |
| 1138 | URU524 | 1996 | 0.25 | 4 | 2/38 | 1 | A9 |
| 1139 | URU708 | 1997 | 0.5 | 4 | 2/38 | 1 | A13 |
| 744 | URU812 | 1997 | 0.25 | 4 | 1/19 | 1 | A5 |
| 745 | URU887 | 1997 | 0.25 | 4 | 1/19 | 1 | A5 |
| 746 | URU888 | 1997 | 0.25 | 4 | 2/38 | 1 | A5 |
| 1140 | URU910 | 1997 | 0.25 | 4 | 2/38 | 1 | A5 |
| 747 | URU954 | 1997 | 0.25 | 4 | 2/38 | 1 | A5 |
| 1141 | URU973 | 1998 | 0.25 | 4 | 1/19 | 1 | A5 |
| 1142 | URU988 | 1998 | 0.25 | 4 | 1/19 | 1 | A5 |
| 1143 | URU1016 | 1998 | 0.25 | 2 | 0.5/9.5 | 4 | A11 |
| 1144 | URU1033 | 1998 | 0.25 | 4 | 2/38 | 1 | A5 |
| 1145 | URU1040 | 1998 | 0.25 | 4 | 1/19 | 1 | A5 |
| 1146 | URU1042 | 1998 | 0.25 | 4 | 1/19 | 1 | A5 |
| 1147 | URU1060 | 1998 | 0.25 | 4 | 1/19 | 1 | A5 |
| 1148 | URU1093 | 1999 | 0.25 | 4 | 2/38 | 1 | A5 |
| 1149 | URU1113 | 1999 | 0.25 | 4 | 1/19 | 1 | A5 |
| 1150 | URU1123 | 1999 | 0.25 | 4 | 1/19 | 2 | A6 |
| 1151 | URU1127 | 1999 | 0.25 | 4 | 1/19 | 1 | A5 |
| 1152 | URU1161 | 1999 | 0.25 | 4 | 1/19 | 1 | A5 |
| 1153 | URU1193 | 1999 | 0.25 | 4 | 0.5/9.5 | 1 | A5 |
| 1154 | URU1205 | 1999 | 0.25 | 4 | 1/19 | 1 | A5 |
| 1155 | URU1208 | 1999 | 0.25 | 4 | 1/19 | 1 | A5 |
| 1156 | URU1213 | 1999 | 0.25 | 4 | 1/19 | 1 | A5 |
| 1157 | URU1215 | 1999 | 0.25 | 4 | 1/19 | 1 | A5 |
ARG: Argentina; BRA: Brazil; COL: Colombia; GUA: Guatemala; MEX: Mexico; URU: Uruguay.
All 172 isolates were susceptible to penicillin, ceftriaxone, erythromycin, and vancomycin. TET, tetracycline resistant (≥8 μg/ml); CHL, chloramphenicol resistant (≥4 μg/ml); STX, trimethoprim-sulfamethoxazole resistant (≥4 μg/ml) and intermediate (1 and 2 μg/ml) (25).
ND, not determined.