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Frequencies of spontaneous and MMC-induced SCEs
| Dose of MMC (ng/ml) | No. of SCEs per cell ± SD
|
|||
|---|---|---|---|---|
| V79 | V-C8 | V-C8+#13 | V-C8+Brca2 | |
| 0 | 6.6 ± 0.4 | 5.4 ± 0.4 | 6.3 ± 0.4 | 5.5 ± 0.3 |
| 0.25 | NDa | 4.8 ± 0.4 | ND | ND |
| 0.5 | ND | 6.9 ± 0.5 | ND | ND |
| 1 | 5.9 ± 0.4 | – | ND | ND |
| 5 | ND | – | 6.9 ± 0.4 | 6.5 ± 0.3 |
| 15 | 15.0 ± 0.7 | – | 8.4 ± 0.5 | 8.5 ± 0.5 |
| 30 | 21.3 ± 1.3 | – | – | – |
ND, not determined; -, not measurable.
