Table 3.
A (controls) | B (clarithromycin) | C (amikacin) | D (clarithromycin + amikacin) | |
Bacterial load (mean ± SE, log10 of cfu/mL) | ||||
Liver | 3.46 ± 0.79 | 3.34 ± 0.89 | 4.19 ± 0.92 | 2.14 ± 0.59 |
Spleen | 3.64 ± 0.75 | 3.63 ± 0.92 | 4.10 ± 0.90 | 3.58 ± 0.79 |
Kidney | 5.94 ± 0.50 | 4.92 ± 0.73 | 6.63 ± 0.30 | 6.82 ± 0.12 |
Lung | 4.73 ± 0.59 | 4.09 ± 0.83 | 6.28 ± 0.39 | 5.76 ± 0.62 |
Pathology score (mean ± SE) | ||||
Liver | 1.25 ± 0.25 | 0.38 ± 0.18a | 0.80 ± 0.20 | 0.71 ± 0.28 |
Spleen | 2.50 ± 0.38 | 2.70 ± 0.37 | 2.80 ± 0.20 | 2.43 ± 0.37 |
Kidney | 2.38 ± 0.46 | 2.13 ± 0.52 | 2.30 ± 0.58 | 2.71 ± 0.36 |
Lung | 1.38 ± 0.32 | 0.75 ± 0.25b | 1.30 ± 0.16 | 1.29 ± 0.29 |
P of comparisons to group A: a0.012, b0.049