Figure 5.

Nucleotide and Deduced Amino Acid Sequence of RTM2 cDNA.

Conceptual translation was started at the first ATG codon. The position of the C-to-T mutation in the rtm2-1 allele is indicated in reverse type. The inverted arrowhead indicates the position of the RTM2 intron in genomic DNA. The sequence with the thin underline is the α-crystallin–like domain. The boxed regions indicate the two types of repeated sequences. The italicized sequence corresponds to the region predicted by the Coils program (Lupas et al., 1991) to possess a continuous α-helical structure. The sequence with the thick underline is the predicted transmembrane sequence. The GenBank accession number for RTM2 is AF208051.