TABLE 3.
Lymphocyte populations in wild-type and p110δ-deficient micea
| Mice | Spleen (n = 8)
|
Peritoneum (n = 8)
|
Lymph nodes (n = 6)
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total cells (106) | Total B cells (%) (B220+) | IgM+ cells (%) | CD4+ T cells (%) | CD8+ T cells (%) | Total cells (106) | B-lineage cells (%) (IgM+) | B1a cells (%) (CD5+ IgM+) | Total cells (106) | Total B cells (%) (B220+) | CD4+ T cells (%) | CD8+ T cells (%) | |
| p110δ+/+ | 47.8 ± 43.0 | 42.3 ± 5.0 | 27.1 ± 4.6 | 19.1 ± 6.1 | 11.6 ± 1.1 | 3.56 ± 0.85 | 31.7 ± 6.2 | 14.0 ± 3.6 | 9.80 ± 3.59 | 31.6 ± 4.5 | 38.7 ± 10.2 | 25.5 ± 3.7 |
| p110δ−/− | 30.4 ± 11.5 | 32.1 ± 11.4 | 20.3 ± 7.3 | 21.7 ± 5.7 | 12.5 ± 3.3 | 1.11 ± 0.28 | 2.4 ± 0.6 | 0.4 ± 0.1 | 6.07 ± 2.14 | 19.0 ± 3.2 | 45.6 ± 4.4 | 27.7 ± 0.8 |
a
See Table 1, footnote a.