Table 4.

Conservation of URE2 C-terminal domains

Species	Identity with S. cerevisiae, %
	Amino acid	DNA	Complementation
S. Paradoxus	100	94	+
S. Bayanus	99	85	+
C. Glabrata	92	78	+
C. Kefyr-1	91	79	+
C. Kefyr-2	91	79	+
K. Lactis	91	77	+
A. gossypii	89	71	−/+*
C. Maltosa	82	73	+
C. Albicans	80	73	+
C. Lipolytica	78	66	−*

Comparison starts at Ser-100 of S. cerevisiae and equivalent positions in other organisms. The sequence from K. lactis was obtained from the GenBank database (gi: 14009513). Complementation is based on expression of the whole sequence with the S. cerevisiae URE2 promoter on a CEN plasmid in YHE888. 

^*Not improved if the URE2 homolog is on a multicopy plasmid.