Table 5.

 Objective effects of intervention. Values are medians (interquartile ranges)

Variable	Intervention group				Control group			Between group significance*
	Baseline	3 months	Change		Baseline	3 months	Change
Gait score†	16 (13 to 17) (n=130)	14 (13 to 16) (n=117)	−1 (−5 to 4) (n=117)		15 (12 to 17) (n=144)	15 (13 to 17) (n=125)	0 (−4 to 4) (n=125)	Baseline P=0.431, 3 months P=0.215, change in score P=0.022
Environmental risk factors	2 (1 to 4) (n=130)	1 (0 to 2) (n=124)	−1 (−4 to 3) (n=124)		2 (1 to 3) (n=144)	2 (1 to 3) (n=135)	−0 (−2 to 2) (n=135)	Baseline P=0.575, 3 months P=0.027, change in score P<0.001
Drop in orthostatic pressure on active standing (mm Hg)‡	−36 (−54 to −27) (n=40)	−12 (−25 to 4) (n=36)	27 (−41 to 92) (n=36)		−38 (−54 to −31) (n=39)	−22 (−43 to −4) (n=34)	19 (−54 to 93) (n=34)	Baseline P=0.388, 3 months P=0.086, change in score P=0.186
Asystole (s)§	4.9 (4.0 to 6.3) (n=18)	0.8 (0.8 to 1.5) (n=14)	−3.5 (−8.1 to 1.1) (n=14)		5.1 (4.6 to 6.3) (n=18)	2.2 (2.0 to 3.3) (n=15)	−1.8 (−5.0 to 1.3) (n=15)	Baseline P=0.834, 3 months P=0.004, change in score P=0.026

^*Mann-Whitney U test. 

^†Gait component of modified performance orientated mobility assessment; lower score better. 

^‡Only patients with orthostatic hypotension on active standing at baseline. 

^§Only patients with cardioinhibitory carotid sinus hypersensitivity at baseline; paced rhythm counted as 0.8 s.