Table 2.
hTERT mRNA expression and hTR in testicular germ cell tumors
| Histology | No. | Telomerase activity Median (25th percentile, 75th percentile) (range) | NhTERT * Median (25th percentile, 75th percentile) (range) |
| ITGCNU | 7 | 0.50 (0.42, 0.53) (0.39–0.55) | 43.1 (29.4, 67.8) (13.0 – 74.0) |
| Seminoma | 13 | 0.45 (0.31, 0.63) (0.19–0.73) | 42.3 (30.9, 50.9) (20.0 – 58.9) |
| EC | 9 | 0.55 (0.47, 0.63) (0.42–0.74) | 73.6 (63.4, 88,7) (56.0 – 99.7) |
| Yolk sac tumor | 4 | 0.39 (0.34, 0.46) (0.3–0.53) | 37.7 (24.8, 49.4) (22.4 – 51.4) |
| Immature teratoma | 6 | 0.52 (0.34–0.70) | 52.6 (42.8, 63.4) (42.5–76.0) |
| Choriocarcinoma | 2 | 0.42 (0.3, 0.55) | 37.6 (32.8 and 42.3) |
| Mature teratoma | 8 | 0.03 (0.01, 0.05) (0.00 – 0.08) | 3.7 (3.1, 4.5) (0 – 6.7) |
EC = Embryonal carcinoma; ITGCNU = intratubular germ cell neoplasia, unclassified in more than 30 % of the tubuli. *Normalized hTERT mRNA expression