Table 2.
Comparison of other studies with information from PLESS
| A. Prostate volume (cm3) | |||||
| PLESS | Other studies (without PLESS) | ||||
| Finasteride | Placebo | Finasteride | Placebo | ||
| Baseline | Number | 157 | 155 | 2719 | 2696 |
| Value | 55.0 | 54.0 | 43.1 | 44.2 | |
| 24 months | Number | 130 | 119 | 2146 | 2140 |
| Value | 45.1 | 58.3 | 31.5 | 41.5 | |
| Mean change from baseline at 24 mths | -9.9 | 4.3 | -10.6 | 3.3 | |
| B. Maximum urinary flow rate (mL/s) | |||||
| PLESS | Other studies (without PLESS) | ||||
| Finasteride | Placebo | Finasteride | Placebo | ||
| Baseline | Number | 1125 | 1127 | 2991 | 2923 |
| Value | 11.0 | 11.0 | 10.5 | 10.3 | |
| 24 months | Number | 786 | 720 | 1806 | 1803 |
| Value | 12.6 | 11.4 | 12.4 | 11.3 | |
| Mean change from baseline at 24 mths | 1.6 | 0.4 | 1.9 | 1.0 | |
Number of patients at baseline, or remained in the studies at 24 months