Figure 2.

Profiles of the free energy (kcal/mol) associated with α/γ transitions as a function of (A) α + γ and (B) α – γ (in degrees); the free energy associated with the canonical conformation is set to 0. Variations of α (red) and γ (green) torsion angle values along the reaction coordinate α + γ and α – γ are shown in (C) and (D), respectively.