Fig. 4.

Neuroprogenitors differentiate into photoreceptor cells. (A) Immunostaining with antibodies to BrdU (green) and rhodopsin (red) showed that the membrane of many BrdU-positive cells contained rhodopsin (arrowheads); the positive cells were located deeply in the developing outer nuclear layer. (B) A smaller number of neuroprogenitors (asterisks) also gave rise to precursors of cone photoreceptor cells, as revealed by double-staining with antibodies to BrdU (green) and cone-specific arrestin (red). (Scale bar: 10 μm.)