Table 3.
Genes with lowered expression in the maturing fibers
| GenBank Accession Number | Gene product | Expression ratio | FDR (ANOVA) | Biological process Signal transduction |
|---|---|---|---|---|
| NM_009790 | Calmodulin 1 (Calm1) | −2.07 | 0.0478 | |
| NM_009861 | Cell division cycle 42 homolog (S. cerevisiae) (Cdc42) | −2.16 | 0.08763 | |
| NM_008760 | Osteoglycin (Ogn) | −2.24 | 0.00242 | |
| NM_010696 | Lymphocyte cytosolic protein 2 (Lcp2) | −2.45 | 0.02637 | |
| NM_054102 | Influenza virus NS1A binding protein (Ivns1abp) | −2.51 | 0.00029 | |
| NM_025618 | Sorcin (Sri) | −2.83 | 0.01369 | |
| NM_011239 | RAN binding protein 1 (Ranbp1) | −2.01 | 0.0193 | |
| Cytoskeleton organization and biogenesis | ||||
| NM_146243 | ARP2 actin-related protein 2 homolog (yeast) (Actr2) | −2.03 | 0.03162 | |
| NM_009510 | Villin 2 (Vil2) | −2.26 | 0.00538 | |
| NM_008538 | Myristoylated alanine rich protein kinase C substrate (Marcks) | −2.12 | 0.00818 | |
| NM_138744 | Synovial sarcoma, X breakpoint 2 interacting protein (Ssx2ip) | −2.29 | 0.00541 | |
| Development and cell differentiation | ||||
| NM_010825 | Myeloid ecotropic viral integration site-related gene 1 (Mrg1/Meis2) | −2.29 | 0.00539 | |
| NM_008885 | Peripheral myelin protein (Pmp22) | −2.36 | 0.03025 | |
| NM_011857 | Odd Oz/10-m homolog 3 (Drosophila) (Odz3) | −2.15 | 0.003 | |
| NM_021881 | Quaking (Qk) | −2.02 | 0.02641 | |
| Cell cycle | ||||
| NM_019914 | ALL1-fused gene from chromosome 1q (Af1q-pending) | −2.11 | 0.01548 | |
| NM_146207 | Cullin 4A (Cul4a) | −2.65 | 0.00173 | |
| NM_015781 | Nucleosome assembly protein 1-like 1 (Nap1l1) | −2.82 | 0.00025 | |
| Transport | ||||
| NM_178405 | ATPase, Na+/K+ transporting, α2 polypeptide (Atp1a2) | −2.08 | 0.00891 | |
| NM_023579 | Karyopherin (importin) β3 (Kpnb3) | −2.83 | 0 | |
| NM_020573 | Oxysterol binding protein-like 1A (Osbpl1a) | −2.10 | 0.0134 | |
| AK083630 | Src activating and signaling molecule (Srcasm) | −3.55 | 0 | |
| NM_009037 | Reticulocalbin (Rcn) | −2.50 | 0.0005 | |
| NM_013703 | Very low density lipoprotein receptor (Vldlr) | −2.10 | 0.03991 | |
| NM_013898 | Translocase of inner mitochondrial membrane 8 homolog a (yeast) (Timm8a) | −2.23 | 0.01784 | |
| Cell adhesion | ||||
| NM_007664 | Cadherin 2 (Cdh2) | −3.74 | 0 | |
| BC034120 | Vitrin (Vit) | −2.08 | 0.00981 | |
| ECM | ||||
| NM_009984 | Cathepsin L (Ctsl) | −2.79 | 0.00029 | |
| J04694 | Procollagen, type IV, α1 (Col4a1) | −2.12 | 0.06809 | |
| Regulation of transcription | ||||
| NM_026003 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (Smarca2) | −3.95 | 0 | |
| BC043450 | Zinc finger protein 198 (Zfp198) | −2.53 | 0.00053 | |
| NM_024186 | Single-stranded DNA binding protein 2 (Ssbp2) | −2.07 | 0.03019 | |
| Metabolism | ||||
| NM_145942 | 3-Hydroxy-3-methylglutaryl-coenzyme A synthase 1 (Hmgcs1) | −2.34 | 0.0361 | |
| NM_019868 | Heterogeneous nuclear ribonucleoprotein H2 (Hnrph2) | −2.10 | 0.07653 | |
| NM_133232 | 6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (Pfkfb3) | −2.42 | 0.00097 | |
| NM_007933 | Enolase 3, β muscle (Eno3) | −2.19 | 0.01283 | |
| NM_145360 | Isopentenyl-diphosphate δ isomerase (Idi1) | −2.55 | 0.00033 | |
| NM_025573 | Splicing factor, arginine/serine rich 9 (Sfrs9) | −2.09 | 0.00778 | |
| NM_053188 | Steroid 5α-reductase 2 (Srd5a2) | −3.32 | 0.00274 | |
| Unknown | ||||
| NM_012056 | FK506 binding protein 9 (Fkbp9) | −2.59 | 0.00778 | |
| NM_026618 | DNA segment, Chr 11, ERATO Doi 99, expressed (D11Ertd99e) | −2.05 | 0.04342 | |
| NM_053194 | Expressed sequence AI114950 (AI114950) | −2.71 | 0.00887 | |
| AK029831 | RIKEN cDNA 6620401M08 gene (6620401M08Rik) | −2.86 | 0.0009 | |
| AK011900 | RIKEN cDNA 2610206D03 gene (2610206D03Rik) | −2.36 | 0.00928 | |
| NM_144846 | RIKEN cDNA 0910001A06 gene (0910001A06Rik) | −2.04 | 0.018 | |
| NM_016809 | RNA binding motif protein 3 (Rbm3) | −2.62 | 0.00016 | |
| AA755091 | RIKEN cDNA 1190005I06 gene (1190005I06Rik) | −2.06 | 0.01361 | |
| NM_023215 | RIKEN cDNA 2500003M10 gene (2500003M10Rik) | −2.10 | 0.00407 | |
| NM_172779 | RIKEN cDNA 6330505F04 gene (6330505F04Rik) | −2.55 | 0.00035 | |
| AK048051 | RIKEN cDNA 1810011E08 gene (1810011E08Rik) | −2.25 | 0.01065 | |
| BC008232 | Mus musculus, clone IMAGE:2647796, mRNA | −2.41 | 0.00105 |
Note: “minus” sign in expression ratio column is used solely to indicate the decrease in expression level.