Table 2.

Expression of cytokines in the lung tissue from C57xCBA mice exposed to 80 mg/m³ SRM2975

Exposure	Air	DEP
Marker		1–6 h	1 day
Tnf	49 ± 19	46 ± 14	149 ± 82**
Il-6	0.47 ± 0.25	5.6 ± 8.1**	2.1 ± 0.52**
Mcp-1	5.3 ± 1.9	18 ± 9.6**	16 ± 11*
Mip-2	23 ± 16	43 ± 37	105 ± 38**
Kc	3.5 ± 2.4	9.4 ± 6.7*	25 ± 18**

Expression of mRNA is normalized to 18S rRNA and is multiplied by 10⁷. Mean ± S.D. is shown (n = 6–11).

*P < 0.05 versus air-exposed mice.

**P < 0.01 versus air-exposed mice.