Table 1.

Summary of disease association results. Number of individuals in the sequencing panel, number of polymorphisms identified per gene, number of tag SNPs selected. Minor allele frequency cut-off used in tag SNP selection, minimum R² of each set of tag SNPs, number of trios analysed, χ² results and multilocus test P values for the IFNA gene cluster, IFNB1, IFNW1 and IFNG.

		Number of
SNP/Gene/Region	Individuals sequenced	Polymorphisms	Tag SNPs	MAF cut-off	Min R2	Trios	χ2	P
IFNA	32	77	20	0.1	0.81	1,335	21.9	0.35
IFNB1	32	11	4	0.05	0.83	1,427	7.2	0.12
IFNW1	32	22	10	0.05	0.88	1,401	4.9	0.90
IFNG	23	7	4	0.1	0.84	1,417	3.8	0.43
IFNG – rs2430561	-	-	-	-	-	1,157	2.9	0.091