Figure 7.

Summary of interactions among proteins involved in mitochondrial gene expression. Thick bars indicate coimmuneprecipitation, double-headed arrows connected by solid lines indicate two-hybrid interactions, and double-headed arrows connected by broken lines indicate genetic/functional interaction. Functional interactions between mitochondrial small subunit ribosomal proteins and Pet122p (McMullin et al., 1990; Haffter et al., 1991; Haffter and Fox, 1992) and interactions between of Nam1p and Rpo41p (mitochondrial RNA polymerase) (Rodeheffer et al., 2001) were reported previously. Two-hybrid and genetic interactions among Pet54p, Pet122p, and Pet494p were reported previously (Brown et al., 1994; Wiesenberger et al., 1995).