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. 2006 Jan 6;90(7):2600–2611. doi: 10.1529/biophysj.105.072587

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Copyright © 2006, Biophysical Society

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Measurement of extracellular sheet resistance in cell adhesion. (a) Fluorescence micrograph of HEK293 cell on a silicon chip coated with fibronectin. The green line marks the periphery of cell adhesion. (b and c) Color-coded maps of amplitude and phase of the negative relative experimental fluorescence modulation at a frequency . The arrows in c limit the region where the phase profiles are measured at various frequencies (see Fig. 6). (d and e) Computed maps of amplitude and phase of transmembrane voltage for a sheet resistance and a dye sensitivity .

Inline graphic — Measurement of extracellular sheet resistance in cell adhesion. (a) Fluorescence micrograph of HEK293 cell on a silicon chip coated with fibronectin. The green line marks the periphery of cell adhesion. (b and c) Color-coded maps of amplitude and phase of the negative relative experimental fluorescence modulation at a frequency . The arrows in c limit the region where the phase profiles are measured at various frequencies (see Fig. 6). (d and e) Computed maps of amplitude and phase of transmembrane voltage for a sheet resistance and a dye sensitivity .