TABLE 1.
Treatment | Plateau force, pN | Escape force, pN | Tether length, μm | Mobile beads, % |
---|---|---|---|---|
HT1080 fibroblasts | ||||
Control | 3.7 ± 0.6 | 8.8 ± 0.5 | 3.0 ± 0.5 | 19 |
Cytochalasin D | 3.1 ± 0.2 | 9.0 ± 0.6 | 12.7 ± 2.3 | 24 |
MβCD | 3.1 ± 0.4 | 7.9 ± 0.4 | 4.9 ± 1.5 | 26 |
Ctochalasin D and MβCD | 2.8 ± 0.2 | 8.2 ± 0.7 | 13.5 ± 2.1 | 27 |
DMSO | 2.8 ± 0.3 | 8.3 ± 0.6 | 17.8 ± 2.7 | 39 |
Mesenchymal stem cells | ||||
Control | 2.9 ± 0.3 | 9.7 ± 0.7 | 10.6 ± 1.1 | 34 |
Cytochalasin D | 2.9 ± 0.2 | 8.8 ± 0.5 | 10.7 ± 2.0 | 61 |
MβCD | 2.8 ± 0.2 | 8.5 ± 0.3 | 16.6 ± 1.9 | 64 |
Cytochalasin D and MβCD | 2.6 ± 0.2 | 7.9 ± 0.6 | 17.9 ± 1.6 | 63 |
DMSO | 2.6 ± 0.2 | 9.0 ± 0.8 | 17.4 ± 3.1 | 58 |