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Correlation between ciprofloxacin MIC and gyrA mutations
| gyrA mutation | No. of isolates inhibited by ciprofloxacin at MIC (mg/liter) of:
|
|||||
|---|---|---|---|---|---|---|
| <0.06 | 0.25 | 0.5 | 1.0 | 2.0 | 4.0 | |
| Asp87-Asn (n = 42) | 9 | 30 | 3 | |||
| Ser83-Phe (n = 38) | 4 | 24 | 3 | 7 | ||
| Asp87-Gly (n = 3) | 1 | 1 | 1 | |||
| Asp87-Tyr (n = 4) | 1 | 3 | ||||
| Ser83-Tyr (n = 12) | 3 | 4 | 2 | 3 | ||
| Wild type (n = 1) | 1 | |||||
| Total (n = 100) | 1 | 11 | 40 | 32 | 6 | 10 |
