Table 2.

Individual contribution (percentage and standard deviation) of CGB, CGB5, CGB7 and CGB8 into summarized chorionic gonadotropin beta subunit determining placental mRNA during the normal pregnancy, in cases of ectopic pregnancy (EP) and recurrent miscarriage (RM).

	Contribution (%) of an individual gene expression in total hCG beta-subunit mRNA
	CGB8		CGB5		CGB		CGB7
	mean ± SD	range	mean ± SD	range	mean ± SD	range	mean ± SD	range
I trimester	39.3±1.8	29–63	25.5±2.7	6–55	27.1±1.5	11–39	8.1±1.2	0–21
II trimester	48.1±2.8***	28–86	25.7±4.2	9–45	20.0±2.3***	1–29	6.2±1.8	0–16
III trimester	39.2±2.5	24–71	36.0±3.8**	7–62	20.1±2.1***	2–32	4.7±1.6**	0–19
ectopic pregnancy	48.0±3.2**	31–62	18.7±4.7	7–28	25.3±2.6	14–54	8.0±2.1	0–17
recurrent miscarriage	47.1±3.7**	28–56	23.3±4.9	13–34	22.0±2.8*	17–27	7.6±2.2	0–13

^***p<0.005

^**p<0.05

^*p<0.08: Significant difference of the expression level of each gene during II and III trimester placentas as well as in cases of EP and RM compared to I trimester of normal pregnancy as a reference level.