TABLE 3.
Comparison of patient signs and symptoms with the median spirochete number
| Sign, symptom, or score | % of patients or score for patients with the following no. of spirochetes:
|
P value | |
|---|---|---|---|
| ≤1,450 (n = 25) | >1,450 (n = 25) | ||
| Loss of appetite | 28 | 28 | 1.000a |
| Dizziness | 16 | 28 | 0.496a |
| Tiredness or lack of energy | 56 | 48 | 0.778a |
| Headache | 32 | 44 | 0.561a |
| Muscle pain | 52 | 40 | 0.571a |
| Joint pain | 36 | 40 | 1.000a |
| Tingling or abnormal sensation | 40 | 16 | 0.114a |
| Stiff neck | 60 | 40 | 0.258a |
| Concentration or memory problems | 32 | 40 | 0.769a |
| Fever or chills | 36 | 32 | 1.000a |
| Cumulative symptom score (median) | 6.2 (1.7-21.6)b | 5.1 (0-25.4) | 0.884c |
| No. of symptoms (median) | 3.0 (1.5-7.5) | 3.0 (0-6) | 0.487c |
| Symptom severity index (median) | 2.6 (1.2-3.3) | 2.9 (0-4.4) | 0.668c |
| Largest EM diameter (cm [median]) | 19 (14-23) | 14 (9-17) | 0.005c |
| Baseline temp (°C, [mean ± SD]) | 36.68 ± 0.6 | 36.86 ± 0.6 | 0.294c |
| Regional lymphadenopathy | 7 | 12 | 0.244d |
a
Fisher's exact test.
b
Values in parentheses are interquartile range (i.e., 25th and 75th percentiles).
c
Mann-Whitney U test.
d
Chi-square test.