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. 2003 Jan;77(1):701–708. doi: 10.1128/JVI.77.1.701-708.2003

FIG. 5.

FIG. 5.

Effects of antibodies on cell-to-cell spread and replication of wild-type and gE− HSV-1 in HEL cells. (A and B) Infected cells were processed for quantification of plaque size after being cultured in the presence of the indicated concentrations of hIgG or anti-gD as described in the legend to Fig. 4. Wild-type HSV-1 plaque size measurements were made at 48 h postinfection, whereas gE− HSV-1 plaque size measurements were made at 72 h postinfection. Results shown are representative of several independent sets of analyses. (C and D) Cells were infected with wild-type or gE− HSV-1 and subsequently cultured in the presence of the indicated concentrations of antibodies. Cell-associated virus titers were estimated 48 h postinfection by plaque assays with Vero cells. Results are representative of two independent sets of analyses.