TABLE 3.

Individual amino acid substitutions for Za and Vs viruses in comparison with 11 tick-borne flaviviruses as revealed by polyprotein alignment

Virus protein	Protein numeration	Polyprotein numeration	Amino acids for other tick-borne flaviviruses	Individual substitutionsa
				Za	Vs
C	73	73	A, L	T
	80	80	K, R	M
PrM	2	115	L, A, M	F
NS1	123	899	M, F, I	V
		279	E, D	G
		294	K	R
NS3	246	1741	A	V
	16	1505	R, Q		K
	64	1553	D, E		N
	186	1675	T, G		M
NS4B	195	2464	A, L, T		V
NS5	195	2706	A	T
	706	3217	E	A
	407	2918	S	N
	51	2562	M, V		T
	202	2713	Q, K		R
	261	2772	V, T		I
	272	2783	K		R
	297	2808	R, K, E, H		G

^aNonconserved amino acid substitutions are in boldface.