FIG. 1.
HIV-1/SIVmac recombinants. The name of the construct reflects the HIV-1 or SIV proviral backbone, and the names in parentheses designate the source of the CA or CA-p2 sequences (H = HIV-1; S = SIVmac). The amino-terminal portions of the Gag polyproteins of the recombinant viruses used in this study are shown beneath the wild-type HIV-1 (white) and SIVmac239 (black) sequences. The locations of the matrix (MA), CA, p2, and NC proteins are shown. The numbers represent the boundaries of the HIV-1 CA sequence that was replaced by the SIVmac sequence. The locations of the N- and C-terminal domains of the CA proteins are shown. The asterisk represents the approximate location of a threonine-to-cysteine change at residue 58 of the HIV-1 CA protein.