TABLE 1.
Viral RNA load comparisonsa
| Time of load detection | Viral RNA load (no. of animals) for:
|
|||
|---|---|---|---|---|
| SIV239 | SIVM5 | SIVΔV1V2 | SIV316 | |
| Peak height (∼ wk 2) | 47 × 106 (10) | 33 × 106 (4) | 7.2 × 105 (2) | 84 × 106 (6) |
| Set point (wk 20-50) | 4.2 × 106 (5) | <2,000 (4) | <100 (2) | <10,000 (6) |
a
Viral loads are expressed as SIV RNA copy equivalents per milliliter of plasma. The numbers denote the averages for the indicated numbers of animals. Two of the 10 SIV239 monkeys used for the peak height averages did not yet have set point data. In addition, three of the SIV239 monkeys were excluded from set point averages because they progressed rapidly to AIDS and death within 6 months and developed soaring (>100 × 106) viral loads. The detection limit for the SIV316 experiments was only 10,000 copies per ml because of the historic nature of the study and the way the samples were stored.