TABLE 5.
Tissue iron stores in adult mice on basal and high-iron dietsa
| Mice | Diet (% iron) | n | Iron level (μg/g) in:
|
|
|---|---|---|---|---|
| Liver | Spleen | |||
| WT | 0.02 | 6 | 231.8 ± 16.6 | 1,339.2 ± 200.4 |
| LFKO−/− | 0.02 | 9 | 234.3 ± 25 | 1,472.9 ± 189 |
| WT | 2.0 | 5 | 2,016.6 ± 155.8 | 2,656.8 ± 429.2 |
| LFKO−/− | 2.0 | 8 | 1,996.4 ± 138.9 | 2,415.8 ± 187.6 |
a
Adult WT and LFKO−/− mice from heterozygote intercrosses were maintained on a basal (0.02% iron) or high-iron (2.0% iron) diet ad libitum for 2 weeks. n, number of mice tested. Values are means and SEMs.