Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
sir2α null mice have abnormal sperm morphology. Spermatozoa from the cauda epididymis were spread on a slide and stained with Dif-Quick stain. (a) Wild-type spermatozoa have a consistent nuclear shape with a characteristic hook. In contrast, the spermatozoa of sir2α null mice (b) had small, rounded, or smudged nuclear shapes. Some had a blunted (arrowhead) or absent hook. The flagella were also variable in shape, and many were no longer attached to sperm heads. Bar, 20 μm.
