FIG. 8.

SNR1^E1 is partially defective for associations with TRX. (A) Genetic interactions between snr1^E1 and trx. The snr1^E1 allele was maternally provided in every cross. Adult flies of each genotype were scored for viability and held-out wings at 18 or 29°C. Values are expressed as the percentages of total adults observed versus number expected for combinations involving snr1^E1 and trx^E2 and percentages of total adults observed with held-out wings. (B) Yeast two-hybrid interaction tests between SNR1 derivatives fused to the GAL4AD and the SET domain (TRX) fused to the GAL4 DNA binding domain. The amino acid regions of SNR1 and TRX included in each fusion are indicated. Interaction ability was determined by lacZ activity (+++, 80 to 100% of full length; ++, 50 to 80%; +, 30 to 50%; −, <30%).